On the Track of DNA Methylation: An Interview with Adrian Bird

Jane Gitschier

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000667

Public Access to Genome-Wide Data: Five Views on Balancing Research with Privacy and Protection

P 3 G Consortium, George Church, Catherine Heeney, Naomi Hawkins, Jantina de Vries, Paula Boddington, Jane Kaye, Martin Bobrow, Bruce Weir

PLOS Genetics: published October 2, 2009 | https://doi.org/10.1371/journal.pgen.1000665

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The Key Role of Genomics in Modern Vaccine and Drug Design for Emerging Infectious Diseases

Kate L. Seib, Gordon Dougan, Rino Rappuoli

PLOS Genetics: published October 26, 2009 | https://doi.org/10.1371/journal.pgen.1000612

Toward the Use of Genomics to Study Microevolutionary Change in Bacteria

Daniel Falush

PLOS Genetics: published October 26, 2009 | https://doi.org/10.1371/journal.pgen.1000627

Progressive GAA·TTC Repeat Expansion in Human Cell Lines

Scott Ditch, Mimi C. Sammarco, Ayan Banerjee, Ed Grabczyk

PLOS Genetics: published October 30, 2009 | https://doi.org/10.1371/journal.pgen.1000704

Acquisition of Aneuploidy Provides Increased Fitness during the Evolution of Antifungal Drug Resistance

Anna M. Selmecki, Keely Dulmage, Leah E. Cowen, James B. Anderson, Judith Berman

PLOS Genetics: published October 30, 2009 | https://doi.org/10.1371/journal.pgen.1000705

Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design?

Iris M. Heid, Cornelia Huth, Ruth J. F. Loos, Florian Kronenberg, Vera Adamkova, Sonia S. Anand, Kristin Ardlie, Heike Biebermann, Peter Bjerregaard, Heiner Boeing, Claude Bouchard, Marina Ciullo, Jackie A. Cooper, Dolores Corella, Christian Dina, James C. Engert, Eva Fisher, Francesc Francès, Philippe Froguel, Johannes Hebebrand, Robert A. Hegele, Anke Hinney, Margret R. Hoehe, Frank B. Hu, Jaroslav A. Hubacek, Steve E. Humphries, Steven C. Hunt, Thomas Illig, Marjo-Riita Järvelin, Marika Kaakinen, Barbara Kollerits, Heiko Krude, Jitender Kumar, Leslie A. Lange, Birgit Langer, Shengxu Li, Andreas Luchner, Helen N. Lyon, David Meyre, Karen L. Mohlke, Vincent Mooser, Almut Nebel, Thuy Trang Nguyen, Bernhard Paulweber, Louis Perusse, Lu Qi, Tuomo Rankinen, Dieter Rosskopf, Stefan Schreiber, Shantanu Sengupta, Rossella Sorice, Anita Suk, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Henry Völzke, Karani S. Vimaleswaran, Nicholas J. Wareham, Dawn Waterworth, Salim Yusuf, Cecilia Lindgren, Mark I. McCarthy, Christoph Lange, Joel N. Hirschhorn, Nan Laird, H.-Erich Wichmann

PLOS Genetics: published October 23, 2009 | https://doi.org/10.1371/journal.pgen.1000694

Inferring the Joint Demographic History of Multiple Populations from Multidimensional SNP Frequency Data

Ryan N. Gutenkunst, Ryan D. Hernandez, Scott H. Williamson, Carlos D. Bustamante

PLOS Genetics: published October 23, 2009 | https://doi.org/10.1371/journal.pgen.1000695

High-Density SNP Screening of the Major Histocompatibility Complex in Systemic Lupus Erythematosus Demonstrates Strong Evidence for Independent Susceptibility Regions

Lisa F. Barcellos, Suzanne L. May, Patricia P. Ramsay, Hong L. Quach, Julie A. Lane, Joanne Nititham, Janelle A. Noble, Kimberly E. Taylor, Diana L. Quach, Sharon A. Chung, Jennifer A. Kelly, Kathy L. Moser, Timothy W. Behrens, Michael F. Seldin, Glenys Thomson, John B. Harley, Patrick M. Gaffney, Lindsey A. Criswell

PLOS Genetics: published October 23, 2009 | https://doi.org/10.1371/journal.pgen.1000696

Loss of Yeast Peroxiredoxin Tsa1p Induces Genome Instability through Activation of the DNA Damage Checkpoint and Elevation of dNTP Levels

Hei-Man Vincent Tang, Kam-Leung Siu, Chi-Ming Wong, Dong-Yan Jin

PLOS Genetics: published October 23, 2009 | https://doi.org/10.1371/journal.pgen.1000697

Quantifying Adaptive Evolution in the Drosophila Immune System

Darren J. Obbard, John J. Welch, Kang-Wook Kim, Francis M. Jiggins

PLOS Genetics: published October 23, 2009 | https://doi.org/10.1371/journal.pgen.1000698

Restricting Dosage Compensation Complex Binding to the X Chromosomes by H2A.Z/HTZ-1

Emily L. Petty, Karishma S. Collette, Alysse J. Cohen, Martha J. Snyder, Györgyi Csankovszki

PLOS Genetics: published October 23, 2009 | https://doi.org/10.1371/journal.pgen.1000699

Bruchpilot in Ribbon-Like Axonal Agglomerates, Behavioral Defects, and Early Death in SRPK79D Kinase Mutants of Drosophila

Vanessa Nieratschker, Alice Schubert, Mandy Jauch, Nicole Bock, Daniel Bucher, Sonja Dippacher, Georg Krohne, Esther Asan, Sigrid Buchner, Erich Buchner

PLOS Genetics: published October 23, 2009 | https://doi.org/10.1371/journal.pgen.1000700

1+1 = 3: A Fusion of 2 Enzymes in the Methionine Salvage Pathway of Tetrahymena thermophila Creates a Trifunctional Enzyme That Catalyzes 3 Steps in the Pathway

Hannah M. W. Salim, Maria Cristina Negritto, Andre R. O. Cavalcanti

PLOS Genetics: published October 23, 2009 | https://doi.org/10.1371/journal.pgen.1000701

Mouse HORMAD1 and HORMAD2, Two Conserved Meiotic Chromosomal Proteins, Are Depleted from Synapsed Chromosome Axes with the Help of TRIP13 AAA-ATPase

Lukasz Wojtasz, Katrin Daniel, Ignasi Roig, Ewelina Bolcun-Filas, Huiling Xu, Verawan Boonsanay, Christian R. Eckmann, Howard J. Cooke, Maria Jasin, Scott Keeney, Michael J. McKay, Attila Toth

PLOS Genetics: published October 23, 2009 | https://doi.org/10.1371/journal.pgen.1000702

Acetylation by the Transcriptional Coactivator Gcn5 Plays a Novel Role in Co-Transcriptional Spliceosome Assembly

Felizza Q. Gunderson, Tracy L. Johnson

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000682

Limiting the Persistence of a Chromosome Break Diminishes Its Mutagenic Potential

Nicole Bennardo, Amanda Gunn, Anita Cheng, Paul Hasty, Jeremy M. Stark

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000683

The Elongator Complex Interacts with PCNA and Modulates Transcriptional Silencing and Sensitivity to DNA Damage Agents

Qing Li, A. M. Fazly, Hui Zhou, Shengbing Huang, Zhiguo Zhang, Bruce Stillman

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000684

Sequential Use of Transcriptional Profiling, Expression Quantitative Trait Mapping, and Gene Association Implicates MMP20 in Human Kidney Aging

Heather E. Wheeler, E. Jeffrey Metter, Toshiko Tanaka, Devin Absher, John Higgins, Jacob M. Zahn, Julie Wilhelmy, Ronald W. Davis, Andrew Singleton, Richard M. Myers, Luigi Ferrucci, Stuart K. Kim

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000685

A Genealogical Interpretation of Principal Components Analysis

Gil McVean

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000686

The Euchromatic and Heterochromatic Landscapes Are Shaped by Antagonizing Effects of Transcription on H2A.Z Deposition

Sara Hardy, Pierre-Étienne Jacques, Nicolas Gévry, Audrey Forest, Marie-Ève Fortin, Liette Laflamme, Luc Gaudreau, François Robert

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000687

A Novel System of Polymorphic and Diverse NK Cell Receptors in Primates

Anne Averdam, Beatrix Petersen, Cornelia Rosner, Jennifer Neff, Christian Roos, Manfred Eberle, Fabienne Aujard, Claudia Münch, Werner Schempp, Mary Carrington, Takashi Shiina, Hidetoshi Inoko, Florian Knaust, Penny Coggill, Harminder Sehra, Stephan Beck, Laurent Abi-Rached, Richard Reinhardt, Lutz Walter

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000688

A Novel Mechanism of Transposon-Mediated Gene Activation

Zhongge Zhang, Milton H. Saier Jr

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000689

A Pol V–Mediated Silencing, Independent of RNA–Directed DNA Methylation, Applies to 5S rDNA

Julien Douet, Sylvie Tutois, Sylvette Tourmente

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000690

Targeted Induction of Endoplasmic Reticulum Stress Induces Cartilage Pathology

M. Helen Rajpar, Ben McDermott, Louise Kung, Rachel Eardley, Lynette Knowles, Mel Heeran, David J. Thornton, Richard Wilson, John F. Bateman, Richard Poulsom, Peter Arvan, Karl E. Kadler, Michael D. Briggs, Raymond P. Boot-Handford

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000691

Expression Quantitative Trait Loci Are Highly Sensitive to Cellular Differentiation State

Alice Gerrits, Yang Li, Bruno M. Tesson, Leonid V. Bystrykh, Ellen Weersing, Albertina Ausema, Bert Dontje, Xusheng Wang, Rainer Breitling, Ritsert C. Jansen, Gerald de Haan

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000692

FON2 SPARE1 Redundantly Regulates Floral Meristem Maintenance with FLORAL ORGAN NUMBER2 in Rice

Takuya Suzaki, Masako Ohneda, Taiyo Toriba, Akiko Yoshida, Hiro-Yuki Hirano

PLOS Genetics: published October 16, 2009 | https://doi.org/10.1371/journal.pgen.1000693

Life on Arginine for Mycoplasma hominis: Clues from Its Minimal Genome and Comparison with Other Human Urogenital Mycoplasmas

Sabine Pereyre, Pascal Sirand-Pugnet, Laure Beven, Alain Charron, Hélène Renaudin, Aurélien Barré, Philippe Avenaud, Daniel Jacob, Arnaud Couloux, Valérie Barbe, Antoine de Daruvar, Alain Blanchard, Cécile Bébéar

PLOS Genetics: published October 9, 2009 | https://doi.org/10.1371/journal.pgen.1000677

From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes

Zhi Wei, Kai Wang, Hui-Qi Qu, Haitao Zhang, Jonathan Bradfield, Cecilia Kim, Edward Frackleton, Cuiping Hou, Joseph T. Glessner, Rosetta Chiavacci, Charles Stanley, Dimitri Monos, Struan F. A. Grant, Constantin Polychronakos, Hakon Hakonarson

PLOS Genetics: published October 9, 2009 | https://doi.org/10.1371/journal.pgen.1000678

Caenorhabditis elegans Myotubularin MTM-1 Negatively Regulates the Engulfment of Apoptotic Cells

Wei Zou, Qun Lu, Dongfeng Zhao, Weida Li, James Mapes, Yuting Xie, Xiaochen Wang

PLOS Genetics: published October 9, 2009 | https://doi.org/10.1371/journal.pgen.1000679

p63 and p73 Transcriptionally Regulate Genes Involved in DNA Repair

Yu-Li Lin, Shomit Sengupta, Katherine Gurdziel, George W. Bell, Tyler Jacks, Elsa R. Flores

PLOS Genetics: published October 9, 2009 | https://doi.org/10.1371/journal.pgen.1000680

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Plasticity of the Chemoreceptor Repertoire in Drosophila melanogaster

Shanshan Zhou, Eric A. Stone, Trudy F. C. Mackay, Robert R. H. Anholt

PLOS Genetics: published October 9, 2009 | https://doi.org/10.1371/journal.pgen.1000681

The Limits of Individual Identification from Sample Allele Frequencies: Theory and Statistical Analysis

Peter M. Visscher, William G. Hill

PLOS Genetics: published October 2, 2009 | https://doi.org/10.1371/journal.pgen.1000628

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Needles in the Haystack: Identifying Individuals Present in Pooled Genomic Data

Rosemary Braun, William Rowe, Carl Schaefer, Jinghui Zhang, Kenneth Buetow

PLOS Genetics: published October 2, 2009 | https://doi.org/10.1371/journal.pgen.1000668

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A Yeast Two-Hybrid Screen for SYP-3 Interactors Identifies SYP-4, a Component Required for Synaptonemal Complex Assembly and Chiasma Formation in Caenorhabditis elegans Meiosis

Sarit Smolikov, Kristina Schild-Prüfert, Mónica P. Colaiácovo

PLOS Genetics: published October 2, 2009 | https://doi.org/10.1371/journal.pgen.1000669

Heterochromatin Protein 1 (HP1a) Positively Regulates Euchromatic Gene Expression through RNA Transcript Association and Interaction with hnRNPs in Drosophila

Lucia Piacentini, Laura Fanti, Rodolfo Negri, Valerio Del Vescovo, Alessandro Fatica, Fabio Altieri, Sergio Pimpinelli

PLOS Genetics: published October 2, 2009 | https://doi.org/10.1371/journal.pgen.1000670

Compensatory Evolution of Gene Regulation in Response to Stress by Escherichia coli Lacking RpoS

Daniel M. Stoebel, Karsten Hokamp, Michael S. Last, Charles J. Dorman

PLOS Genetics: published October 2, 2009 | https://doi.org/10.1371/journal.pgen.1000671

Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations

Andrew A. Hicks, Peter P. Pramstaller, Åsa Johansson, Veronique Vitart, Igor Rudan, Peter Ugocsai, Yurii Aulchenko, Christopher S. Franklin, Gerhard Liebisch, Jeanette Erdmann, Inger Jonasson, Irina V. Zorkoltseva, Cristian Pattaro, Caroline Hayward, Aaron Isaacs, Christian Hengstenberg, Susan Campbell, Carsten Gnewuch, A. CecileJ.W. Janssens, Anatoly V. Kirichenko, Inke R. König, Fabio Marroni, Ozren Polasek, Ayse Demirkan, Ivana Kolcic, Christine Schwienbacher, Wilmar Igl, Zrinka Biloglav, Jacqueline C. M. Witteman, Irene Pichler, Ghazal Zaboli, Tatiana I. Axenovich, Annette Peters, Stefan Schreiber, H.-Erich Wichmann, Heribert Schunkert, Nick Hastie, Ben A. Oostra, Sarah H. Wild, Thomas Meitinger, Ulf Gyllensten, Cornelia M. van Duijn, James F. Wilson, Alan Wright, Gerd Schmitz, Harry Campbell

PLOS Genetics: published October 2, 2009 | https://doi.org/10.1371/journal.pgen.1000672

Epigenetic and Conventional Regulation Is Distributed among Activators of FLO11 Allowing Tuning of Population-Level Heterogeneity in Its Expression

Leah M. Octavio, Kamil Gedeon, Narendra Maheshri

PLOS Genetics: published October 2, 2009 | https://doi.org/10.1371/journal.pgen.1000673

Inference of Microbial Recombination Rates from Metagenomic Data

Philip L. F. Johnson, Montgomery Slatkin

PLOS Genetics: published October 2, 2009 | https://doi.org/10.1371/journal.pgen.1000674

Requirements for F-BAR Proteins TOCA-1 and TOCA-2 in Actin Dynamics and Membrane Trafficking during Caenorhabditis elegans Oocyte Growth and Embryonic Epidermal Morphogenesis

Chiara Giuliani, Flavia Troglio, Zhiyong Bai, Falshruti B. Patel, Adriana Zucconi, Maria Grazia Malabarba, Andrea Disanza, Theresia B. Stradal, Giuseppe Cassata, Stefano Confalonieri, Jeffrey D. Hardin, Martha C. Soto, Barth D. Grant, Giorgio Scita

PLOS Genetics: published October 2, 2009 | https://doi.org/10.1371/journal.pgen.1000675

Oncogenic Pathway Combinations Predict Clinical Prognosis in Gastric Cancer

Chia Huey Ooi, Tatiana Ivanova, Jeanie Wu, Minghui Lee, Iain Beehuat Tan, Jiong Tao, Lindsay Ward, Jun Hao Koo, Veena Gopalakrishnan, Yansong Zhu, Lai Ling Cheng, Julian Lee, Sun Young Rha, Hyun Cheol Chung, Kumaresan Ganesan, Jimmy So, Khee Chee Soo, Dennis Lim, Weng Hoong Chan, Wai Keong Wong, David Bowtell, Khay Guan Yeoh, Heike Grabsch, Alex Boussioutas, Patrick Tan

PLOS Genetics: published October 2, 2009 | https://doi.org/10.1371/journal.pgen.1000676

Dissection of the Complex Phenotype in Cuticular Mutants of Arabidopsis Reveals a Role of SERRATE as a Mediator

Derry Voisin, Christiane Nawrath, Sergey Kurdyukov, Rochus B. Franke, José J. Reina-Pinto, Nadia Efremova, Isa Will, Lukas Schreiber, Alexander Yephremov

PLOS Genetics: published October 30, 2009 | https://doi.org/10.1371/journal.pgen.1000703