Figures
Fig 6 is incorrect. Magnified images do not appear in the figure. The publisher apologizes for the error. The authors have provided a corrected version of Fig 6 here.
(A) Heatmap representing the top 55 directly TFAP2-activated genes and (B) the top 55 directly TFAP2-inhibited genes that are associated with the GO terms cell pigmentation and cell-cell adhesion, respectively. Four replicate RNA-Seq experiments are shown for WT cells and two clones of TFAP2-KO cells (Clone 2.12 and Clone 4.3) (FDR < 0.05). (C) Growth curves (mean ± SE of mean) over 100 hours of cultivation for WT and TFAP2-KO SK-MEL-28 cells. x-axis is time and y-axis is absorbance at 450nm which is directly proportional to number of living. (D) Box plots representing the quantification of cluster formation on low-bind plates after 72 hours of culture (n = 12 independent experiments, p < 0.001 by Student’s t-test, plot shows mean ± SD). (E) Representative images of clusters formed in WT and TFAP2-KO cells after 72 hours.
Reference
- 1. Kenny C, Dilshat R, Seberg HE, Van Otterloo E, Bonde G, Helverson A, et al. (2022) TFAP2 paralogs facilitate chromatin access for MITF at pigmentation and cell proliferation genes. PLoS Genet 18(5): e1010207. https://doi.org/10.1371/journal.pgen.1010207 pmid:35580127
Citation: The PLOS Genetics Staff (2022) Correction: TFAP2 paralogs facilitate chromatin access for MITF at pigmentation and cell proliferation genes. PLoS Genet 18(8): e1010378. https://doi.org/10.1371/journal.pgen.1010378
Published: August 29, 2022
Copyright: © 2022 The PLOS Genetics Staff . This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.