Figures
Congenital idiopathic megaesophagus in the German shepherd dog is a sex-differentiated trait and is associated with an intronic variable number tandem repeat in Melanin-Concentrating Hormone Receptor 2
Maxx is a German shepherd dog affected by a gastrointestinal motility disorder termed megaesophagus. During and following meals, Maxx sits in a chair designed to keep his esophagus vertical, thereby promoting the passage of food into his stomach. Bell et al. uncovered a male sex bias and identified a variable number tandem repeat, intronic to MCHR2, that is strongly associated with congenital idiopathic megaesophagus in German shepherd dogs. See Bell et al.
Download March's cover page.
Image Credit: Kathleen O'Sullivan, https://www.katophotographywilm.com
Citation: (2022) PLoS Genetics Issue Image | Vol. 18(3) March 2022. PLoS Genet 18(3): ev18.i03. https://doi.org/10.1371/image.pgen.v18.i03
Published: March 31, 2022
This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
Maxx is a German shepherd dog affected by a gastrointestinal motility disorder termed megaesophagus. During and following meals, Maxx sits in a chair designed to keep his esophagus vertical, thereby promoting the passage of food into his stomach. Bell et al. uncovered a male sex bias and identified a variable number tandem repeat, intronic to MCHR2, that is strongly associated with congenital idiopathic megaesophagus in German shepherd dogs. See Bell et al.
Download March's cover page.
Image Credit: Kathleen O'Sullivan, https://www.katophotographywilm.com