Figures
Nucleocytoplasmic transport and nuclear membrane expansion are critical for nuclear size control.
How membrane-bound organelles are maintained at an appropriate size during cell growth and division is poorly understood. The simply shaped S. pombe nucleus undergoes a closed mitosis in a single copy within a cell, making it a useful system for studying organelle size homeostasis. Kume et al. carried out a near genome-wide screen for fission yeast mutants with altered nuclear size and show that nucleocytoplasmic transport and appropriately regulated nuclear membrane expansion are central to nuclear size control. Shown here are the nuclear envelopes of wild-type (cyan) and nuclear size mutant (green) fission yeast cells. See Kume et al.
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Image Credit: Kazunori Kume, Hiroshima University
Citation: (2017) PLoS Genetics Issue Image | Vol. 13(5) May 2017. PLoS Genet 13(5): ev13.i05. https://doi.org/10.1371/image.pgen.v13.i05
Published: May 31, 2017
Copyright: © 2017 Kazunori Kume. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
How membrane-bound organelles are maintained at an appropriate size during cell growth and division is poorly understood. The simply shaped S. pombe nucleus undergoes a closed mitosis in a single copy within a cell, making it a useful system for studying organelle size homeostasis. Kume et al. carried out a near genome-wide screen for fission yeast mutants with altered nuclear size and show that nucleocytoplasmic transport and appropriately regulated nuclear membrane expansion are central to nuclear size control. Shown here are the nuclear envelopes of wild-type (cyan) and nuclear size mutant (green) fission yeast cells. See Kume et al.
Download May's cover page here.
Image Credit: Kazunori Kume, Hiroshima University