Figures
Anterior development during early mouse embryogenesis.
Holoprosencephaly is a severe genetic disease affecting human brain and craniofacial development. The work by Taniguchi et al. demonstrates that Tgif1, a gene implicated in human holoprosencephaly, is involved in regulating Sonic Hedgehog signaling and forebrain development during early mouse embryogenesis. This image shows a scanning electron micrograph of the frontal view of a normal mouse embryo at nine days post fertilization.
Image Credit: Kenichiro Taniguchi and David Wotton (University of Virginia).
Citation: (2012) PLoS Genetics Issue Image | Vol. 8(2) February 2012. PLoS Genet 8(2): ev08.i02. https://doi.org/10.1371/image.pgen.v08.i02
Published: February 23, 2012
Copyright: © 2012 Taniguchi and Wotton. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Holoprosencephaly is a severe genetic disease affecting human brain and craniofacial development. The work by Taniguchi et al. demonstrates that Tgif1, a gene implicated in human holoprosencephaly, is involved in regulating Sonic Hedgehog signaling and forebrain development during early mouse embryogenesis. This image shows a scanning electron micrograph of the frontal view of a normal mouse embryo at nine days post fertilization.
Image Credit: Kenichiro Taniguchi and David Wotton (University of Virginia).