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PLoS Genetics Issue Image | Vol. 7(12) December 2011

A Chinese Silkie rooster exhibiting fibromelanosis.

The study of Dorshorst et al. shows that fibromelanosis (intense pigmentation of the dermal layer of skin and pigmented connective tissue) is caused by a complex genomic rearrangement that leads to upregulated expression of the Endothelin 3 gene located within the rearranged region. The study illustrates how structural changes have contributed to rapid phenotypic evolution in domestic animals.

Image Credit: Freyja Imsland (Uppsala University)

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A Chinese Silkie rooster exhibiting fibromelanosis.

The study of Dorshorst et al. shows that fibromelanosis (intense pigmentation of the dermal layer of skin and pigmented connective tissue) is caused by a complex genomic rearrangement that leads to upregulated expression of the Endothelin 3 gene located within the rearranged region. The study illustrates how structural changes have contributed to rapid phenotypic evolution in domestic animals.

Image Credit: Freyja Imsland (Uppsala University)

https://doi.org/10.1371/image.pgen.v07.i12.g001