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PLoS Genetics Issue Image | Vol. 5(12) December 2009

A colony of the pathogenic yeast Candida albicans grown on CHROMagar medium exhibits complex colony morphology.

In this issue of PLoS Genetics, Homann et al. report a phenotypic profile of the transcriptional network of Candida albicans. A library of transcription factor deletion strains was created and tested for growth and colony morphology phenotypes on over 50 different growth media. The resulting phenotypic profiles provide insight into the cellular role of many previously uncharacterized transcription factors and also provide new insight into the scope of the regulatory network governing the creation of complex colony morphologies in C. albicans.

Image Credit: Oliver Homann and Jeanselle Dea

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A colony of the pathogenic yeast Candida albicans grown on CHROMagar medium exhibits complex colony morphology.

In this issue of PLoS Genetics, Homann et al. report a phenotypic profile of the transcriptional network of Candida albicans. A library of transcription factor deletion strains was created and tested for growth and colony morphology phenotypes on over 50 different growth media. The resulting phenotypic profiles provide insight into the cellular role of many previously uncharacterized transcription factors and also provide new insight into the scope of the regulatory network governing the creation of complex colony morphologies in C. albicans.

Image Credit: Oliver Homann and Jeanselle Dea

https://doi.org/10.1371/image.pgen.v05.i12.g001