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Genome and proteome analysis of Sahara bacterium Deinococcus deserti.
Genome annotation of Deinococcus deserti, a species isolated from Sahara surface sand, was performed in parallel with proteome analysis. Proteomics and comparative genomics allowed for the correction of several gene prediction errors, which were also present in previously sequenced Deinococcus species. This work demonstrates that accurate primary genome annotation is obtained when a combination of high-throughput proteomic and genomic techniques is used (see de Groot et al., doi:10.1371/journal.pgen.1000434). Remarkably, D. deserti has three recA genes and three lesion-bypass DNA polymerases, which probably contribute to survival in its dry and ultraviolet-exposed extreme environment.
Image Credit: Photo of rocks and sand in the Sahara by Suzanne Sommer (Université Paris Sud, France).
Citation: (2009) PLoS Genetics Issue Image | Vol. 5(3) March 2009. PLoS Genet 5(3): ev05.i03. https://doi.org/10.1371/image.pgen.v05.i03
Published: March 27, 2009
Copyright: © 2009 Suzanne Sommer. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Genome annotation of Deinococcus deserti, a species isolated from Sahara surface sand, was performed in parallel with proteome analysis. Proteomics and comparative genomics allowed for the correction of several gene prediction errors, which were also present in previously sequenced Deinococcus species. This work demonstrates that accurate primary genome annotation is obtained when a combination of high-throughput proteomic and genomic techniques is used (see de Groot et al., doi:10.1371/journal.pgen.1000434). Remarkably, D. deserti has three recA genes and three lesion-bypass DNA polymerases, which probably contribute to survival in its dry and ultraviolet-exposed extreme environment.
Image Credit: Photo of rocks and sand in the Sahara by Suzanne Sommer (Université Paris Sud, France).