Figures
The Drosophila salivary gland is used to assay tissue-specific responses to steroids in a whole-animal context
Pictured is a confocal image of live cells from a larval gland expressing a DsRED-tagged protein loaded into secretory granules and a GFP-tagged reporter protein localized to the nucleus. For the RED cargo to be synthesized and secreted, the tissue must be exposed to two different pulses of hormone. These steroid signals are also mediated by two distinct functional receptors, only one of which was previously characterized (see Costantino et al., doi:10.1371/journal.pgen.1000102).
Image Credit: Image generated by Benjamin F. B. Costantino and Daniel K. Bricker.
Citation: (2008) PLoS Genetics Issue Image | Vol. 4(6) June 2008. PLoS Genet 4(6): ev04.i06. https://doi.org/10.1371/image.pgen.v04.i06
Published: June 27, 2008
Copyright: © 2008 Costantino et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Pictured is a confocal image of live cells from a larval gland expressing a DsRED-tagged protein loaded into secretory granules and a GFP-tagged reporter protein localized to the nucleus. For the RED cargo to be synthesized and secreted, the tissue must be exposed to two different pulses of hormone. These steroid signals are also mediated by two distinct functional receptors, only one of which was previously characterized (see Costantino et al., doi:10.1371/journal.pgen.1000102).
Image Credit: Image generated by Benjamin F. B. Costantino and Daniel K. Bricker.