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PLoS Genetics Issue Image | Vol. 4(2) February 2008

Blimp1:gfp primordial germ cells

At embryonic day 7.5, most XX primordial germ cells show an inactive X chromosome like their somatic neighbour cells. Blimp1:gfp primordial germ cells (green) after 2 days of culture showing a distinct trimetylation of histone 3 on lysine 27 (H3K27me3) nuclear accumulation (pink) indicative of the inactive X chromosome (see Chuva de Sousa Lopes et al., e30).

Image Credit: Confocal micrograph provided by Susana Chuva de Sousa Lopes and Katsuhiko Hayashi

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Blimp1:gfp primordial germ cells

At embryonic day 7.5, most XX primordial germ cells show an inactive X chromosome like their somatic neighbour cells. Blimp1:gfp primordial germ cells (green) after 2 days of culture showing a distinct trimetylation of histone 3 on lysine 27 (H3K27me3) nuclear accumulation (pink) indicative of the inactive X chromosome (see Chuva de Sousa Lopes et al., e30).

Image Credit: Confocal micrograph provided by Susana Chuva de Sousa Lopes and Katsuhiko Hayashi

https://doi.org/10.1371/image.pgen.v04.i02.g001