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PLoS Genetics Issue Image | Vol. 3(12) December 2007

Defects in zebrafish embryos

Expression of mutant Shp2 with a mutation that was identified in human Noonan Syndrome results in a range of defects in zebrafish embryos, including shortening of the body axis (top three embryos) compared to a control non-injected embryo (bottom) (see Jopling et al., e225).

Image Credit: Photograph provided by Chris Jopling, Hubrecht Institute.

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Defects in zebrafish embryos

Expression of mutant Shp2 with a mutation that was identified in human Noonan Syndrome results in a range of defects in zebrafish embryos, including shortening of the body axis (top three embryos) compared to a control non-injected embryo (bottom) (see Jopling et al., e225).

Image Credit: Photograph provided by Chris Jopling, Hubrecht Institute.

https://doi.org/10.1371/image.pgen.v03.i12.g001