Figures
Mammalian genomic imprinting
The platypus (a monotreme) diverged from therian (marsupial and eutherian) mammals approximately 170 million years ago (MYA). Marsupials and eutherians separated about 125 MYA. By comparing the genomic sequence of a specific imprinted domain between these extant mammals, it is clear that imprinting in this region arose only after insertion of the retrotransposon-derived gene PEG10 around 125 MYA (see Suzuki et al., e55).
Image Credit: Photographs provided by D. Parer and E. Parer-Cook (platypus), the Australian Broadcasting Corporation Natural History Unit and M. B. Renfree (wallaby), and the University of Melbourne. Cover design by G. Shaw, University of Melbourne.
Citation: (2007) PLoS Genetics Issue Image | Vol. 3(4) April 2007. PLoS Genet 3(4): ev03.i04. https://doi.org/10.1371/image.pgen.v03.i04
Published: April 27, 2007
Copyright: © 2007 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The platypus (a monotreme) diverged from therian (marsupial and eutherian) mammals approximately 170 million years ago (MYA). Marsupials and eutherians separated about 125 MYA. By comparing the genomic sequence of a specific imprinted domain between these extant mammals, it is clear that imprinting in this region arose only after insertion of the retrotransposon-derived gene PEG10 around 125 MYA (see Suzuki et al., e55).
Image Credit: Photographs provided by D. Parer and E. Parer-Cook (platypus), the Australian Broadcasting Corporation Natural History Unit and M. B. Renfree (wallaby), and the University of Melbourne. Cover design by G. Shaw, University of Melbourne.