Figures
Partial inhibition of Hsp90
The images illustrate the phenotypic spectrum, uncovered in one zebrafish strain, following partial inhibition of Hsp90. The frequency and range of severity observed after inbreeding suggests involvement of multiple genes and thresholds. The microphthalmia and anophthalmia are reminiscent of similar human malformations, often unilateral and without clear inheritance patterns (see see Yeyati et al., e43).
Image Credit: Photographs by Patricia L. Yeyati.
Citation: (2007) PLoS Genetics Issue Image | Vol. 3(3) March 2007. PLoS Genet 3(3): ev03.i03. https://doi.org/10.1371/image.pgen.v03.i03
Published: March 30, 2007
Copyright: © 2007 Yeyate et al.. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The images illustrate the phenotypic spectrum, uncovered in one zebrafish strain, following partial inhibition of Hsp90. The frequency and range of severity observed after inbreeding suggests involvement of multiple genes and thresholds. The microphthalmia and anophthalmia are reminiscent of similar human malformations, often unilateral and without clear inheritance patterns (see see Yeyati et al., e43).
Image Credit: Photographs by Patricia L. Yeyati.