Table 1.
Samples included in this study.
Fig 1.
Internal Iranian population structure.
Relative sample locations with respect to the first two MDS components. (A) Relative sample locations of the Iranian ethnic groups from this study, including 90% density limits; (B) zoomed view into the subset of the seven groups belonging to the Central Iranian Cluster (CIC).
Fig 2.
Iranian ethnic groups in a global context.
Relative sample locations with respect to the first two MDS components. Iranian ethnic groups in a global context (subset of “Old World” populations from the global 1000G data set); inlet zoomed view of the CIC and adjacent European populations.
Fig 3.
Iranian ethnic groups in a regional context.
Relative sample locations with respect to the first two MDS components. Iranian ethnic groups (solid points) in a local context of samples from [2, 6, 44] (open symbols, triangles and 90% density limits).
Table 2.
Assessment of population substructure.
Fig 4.
ADMIXTURE inference of Iranian ethnic groups.
(A) Inference in Iranian data set. Inferred mixture proportions for 1021 Iranian samples from this study for k = 4 ancestral populations, yielding a minimal cross-validation (CV) error of 0.544; (B) Inference in global data set. Additional inclusion of the global 1000G data set (k = 13; CV = 0.499). (C) Inference in local data set. Additional inclusion of the local data set (k = 8; CV = 0.575).
Fig 5.
Ancient DNA samples from 45,000 (Upper Palaeolithic)–3350 BCE in the context of extant Iranian ethnic groups.
Time-period specific ancient DNA samples (S3 Table) projected onto extant human variation (S18 Fig). The geographic origin of the ancient samples is coded by color.
Fig 6.
Ancient DNA samples from 3350–1200 BCE in the context of extant Iranian ethnic groups.
Time-period specific ancient DNA samples (S3 Table) projected onto extant human variation (S18 Fig). The geographic origin of the ancient samples is coded by color. Previous time strata are indicated by 95% density limits (refer to Fig 5).
Fig 7.
Ancient DNA samples from 1200 BCE–1460 CE in the context of extant Iranian ethnic groups.
Time-period specific ancient DNA samples (S3 Table) projected onto extant human variation (S18 Fig). The geographic origin of the ancient samples is coded by color. Previous time strata are indicated by 95% density limits (refer to Figs 5 and 6).
Table 3.
Comparative consanguinity assessment.