Fig 1.
Manhattan plots for (A) FC-AS and (B) MC-FS analyses. The horizontal lines denote the genome-wide significance cutoff of 5.0e-8 and a suggestive cutoff of 1.0e-6.
Fig 2.
Associations at two genome-wide significant loci.
(A) Association with FC-AS at 10q11.22. (B) Association with MC-FS at 2p22.2. (C-D) Associations with each coder’s attractiveness ratings at two genome-wide significant loci. Each interval shows the association with attractiveness score given by one coder. Error bars denote 95% confidence intervals of effect estimates. To maintain sufficient sample size, only coders who rated more than 500 male samples were included in MS studies and coders who rated more than 500 female samples were included in FS studies.
Table 1.
Genome-wide significant loci associated with facial attractiveness.
Fig 3.
Selection signatures of facial attractiveness.
SNPs with MAF between 0.05 and 0.5 were grouped into 10 equally-sized bins based on MAF quantiles. For SNPs in each bin, average MAF was calculated shown on the x-axis, while the average minor allele effects are shown on the y-axis.
Fig 4.
Genetic covariance between facial attractiveness and (A) BMI traits, (B) lipid traits. Intervals show the 95% confidence intervals of covariance estimates. Genetic covariance with fdr < 0.1 are marked by one asterisk and the covariance with p-value < 1e-4 is marked by two asterisks.