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Figure 1.

Modes of cell growth and polyploidy in mammals.

(A) Diagram depicting different mechanisms underlying the formation of polyploid cells ranging from fusion of post-mitotic diploid cells, endomitosis (nuclear but not cell division), and endoreduplication. (B) Nuclei of polyploid trophoblast giant cells show selected small regions of under-replication (based on results from Hannibal et al.).

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