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Table 1.

Data summary.

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Table 2.

Type-1 Error for the three approaches: collapsing (C), weighted-sum (WS), and replication-based (R).

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Table 3.

Power Estimates () for the three approaches: collapsing (C) versus weighted-sum (WS) versus replication-based (R).

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Table 4.

Power Estimates () for two-sided tests, testing for the presence of risk or protective variants, when there is a mixture of risk and protective variants in the region of interest.

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Table 5.

Type-1 diabetes results.

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