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Figure 1.

Circular Representation of the Closed Genome of Kp342.

The chromosome (A) is illustrated as a circle where each concentric circle represents genomic data and is numbered from the outermost to the innermost circle. Refer to the key for details on color representations and circle number. The comparisons to E. coli K12 (circle 5) and MGH78578 (circle 4) are noted as follows. The color indicates the position of the matching Kp342 region (circle 2) using NUCMER. The height of the tick indicates the percent identity of the NUCMER match. Plasmids pKP187 (B) and pKP91 (C) are likewise depicted circular, but each concentric circle from 4 to the innermost circle shows the NUCMER match to previously sequenced plasmids from NCBI, colored by the percent identity of the matching region. See key for color conversion.

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Table 1.

Genome Features of Klebsiella pneumoniae 342.

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Figure 2.

Whole-Genome Comparison of Kp342 to K. pneumoniae MGH78578 and E. coli K12.

Line figures depict the results of NUCMER analysis. Colored lines denote nucleotide percent identity and are plotted according to the location in the reference Kp342 genome (x-axis) and the query genomes K. pneumoniae MGH78578 (A) and E. coli K12 (B).

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Figure 3.

Whole Genome Comparison of K. pneumoniae 342, K. pneumoniae MGH78578, and E. coli K12 Proteins.

The Venn diagram shows the number of proteins shared (black) or unique (red) within a particular relationship for all three organisms compared.

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Table 2.

Lawlor et al. Signature-tagged Mutants Present in One Strain but Lacking from the Other*.

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Table 3.

Infection of Kp342 and Clinical Strain K. pneumoniae C3091 in Mouse Urinary Tract Infection and Lung Infection Models.

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Table 4.

Kp342 Antibiotic Resistance Profile.

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