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Considerations for homology-based DNA repair in mosquitoes: Impact of sequence heterology and donor template source

Fig 3

Characteristics of gene conversion tracts in perfect repair events generated with constructs 190-recoded (red bar) and 234-recoded (purple bar).

Positions of SNPs within the homology arms, relative to the cut sites for 190-recoded and 234-recoded, are marked with red and purple vertical lines, respectively (See Tables C and D in S1 File for specific nucleotide changes introduced). Count of HDR events indicates the number of individuals, and independent pools from which a conversion of that size range was recovered. Error bars indicate the range of possible conversion tract lengths which could not be detected by sequencing.

Fig 3

doi: https://doi.org/10.1371/journal.pgen.1010060.g003