Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB cooperate for developmental stability
Fig 5
Genes deregulated in wing imaginal discs expressing CycGΔP.
A–RT-qPCR analysis of endogenous CycG expression in da-Gal4,UAS-CycGΔP/+ and da-Gal4/+ wing imaginal discs. Expression of CycG was normalized on the geometric mean of Lam and rin (S8 Table). t-tests, ** p-value<0.01. Error bars correspond to standard deviations. B–Ontology of up-regulated and down-regulated genes in da-Gal4, UAS-CycGΔP/+ vs da-Gal4/+ wing imaginal discs. Gene ontology analysis was performed with DAVID (S9 Table). C–RT-qPCR analysis of RPL15, RPL7 and Rack1 expression in da-Gal4, UAS-CycGΔP/+ and da-Gal4/+ wing imaginal discs. Expression of RPL15, RPL7 and Rack1 were normalized on the geometric mean of Lam and rin (S10 Table). t-tests, ** p-value<0.01. Error bars correspond to standard deviations. t-tests, ** p-value<0.01; *** p-value<0.001.