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OFF-responses of interneurons optimize avoidance behaviors depending on stimulus strength via electrical synapses

Fig 4

AIB calcium increases probability of omega turns.

(A) AIB expressing HisCl1 (AIB::HisCl) inhibits omega turns in the presence of histamine. n = 4,6,16,7,4,5,16,5. n = plate (cohort) of approximately 10–20 animals. The data are presented as the mean ± SEM. (B) ChR2-induced excitation of AIB (AIB::ChR2(H134R)) increases omega turns during and after the 2-sec stimulation. n = 49, 57. n means the number of individuals (animals). (C) AVA expressing HisCl1 (AVA::HisCl) inhibits all avoidance behaviors in the presence of histamine. n = 6,6,7,7,6,6. n = plate (cohort) of approximately 10–20 animals. The data are presented as the mean ± SEM.

Fig 4

doi: https://doi.org/10.1371/journal.pgen.1007477.g004