Evaluation and application of summary statistic imputation to discover new height-associated loci
Fig 5
Summary statistics imputation versus genotype imputation for null variants.
The x-axis shows the Z-statistics of the genotype data (ground truth), while the y-axis shows the Z-statistics from summary statistics imputation (green) or genotype imputation (blue). Results are grouped according to MAF (columns) and imputation quality (rows) categories and the numbers top-right in each window refers to the number of SNVs represented. The identity line is indicated with a dotted line. The estimation for correlation and slope are noted in the bottom-right corner for summary statistics imputation and in the top-left corner for genotype imputation. Blue dots are plotted over the green ones. S12 and S14 Figs provide scatterplots with the imputation quality of summary statistics imputation and genotype imputation as colors.