The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene

doi:10.1371/journal.pgen.1005672

The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene

Fig 4

The differences in H2-Ab1 AA sequences between B6.I-100 and B6.I-139 mice.

Protein structure alignment of H2-Ab1molecules. Gene annotations are from UniProt Domain structure http://www.uniprot.org: 1–27 –signal peptide; 28–122 - β1 polymorphic domain; 123–216 - β2 conservative domain; 217–226 –connecting peptide (CP); 227–247 –transmembrane domain (TM); 248–265 –cytoplasmic domain (CD). H2^{b –}H2^j AA substitutions are highlighted.

doi: https://doi.org/10.1371/journal.pgen.1005672.g004