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24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex

Figure 1

Representative cycling and non-cycling DNA methylation sites.

Hash marks indicate means and 95% confidence intervals of the mean. Data are double plotted in 4 hour bins. Red line indicates best-fit cosine curve. (A,B) representative rhythmic DNA methylation sites. (C,D) representative arrhythmic DNA methylation sites. Abbreviations: PVE proportion of variance explained.

Figure 1

doi: https://doi.org/10.1371/journal.pgen.1004792.g001