A Network of HMG-box Transcription Factors Regulates Sexual Cycle in the Fungus Podospora anserina
Figure 2
Unrooted phylogram for the HMG-box superfamily.
Clustering of core amino acid sequences using maximum-likelihood and model LG+G [107]. Color labeling: MATα_HMG (A, green), MATA_HMG (B, yellow), SOX-TCF_HMG (C, orange), HMGB-UBF_HMG (D, H, blue), MAT1-1-3 in MATA_HMG (E, white) and STE11 in MATA_HMG (G, red). Other labels: Microsporidia MAT sex locus in HMGB-UBF_HMG (F, grey), Phycomyces blakesleeanus (Zygomycota) sexM (Phybl8) and sexP (Phybl9) (purple) and P. anserina proteins (red dots). LR-ELW values greater than 70% are shown. Abbreviations: Ailuropoda melanoleuca (Ailme); Ajellomyces capsulatus (Ajeca); Alternaria alternata (Altal); Alternaria brassicicola (Altbr); Anopheles gambiae (Anoga); Antonospora locustae (Antlo); Arabidopsis thaliana (Arath); Aspergillus fumigatus (Aspfu); Aspergillus nidulans (Aspni); Botryotinia fuckeliana (Botfu); Bipolaris sacchari (Bipsa); Caenorhabditis elegans (Caeel); Candida albicans (Canal); Cervus elaphus yarkandensis (Cerel); Ciona savignyi (Ciosa); Cochliobolus heterostrophus (Coche); Cochliobolus homomorphus (Cocho); Coprinopsis cinerea (Copci); Cryphonectria parasitica (Crypa); Culex quinquefasciatus (Culqu); Danio rerio (Danre); Dothistroma pini (Dotpi); Drosophila melanogaster (Drome); Enterocytozoon bieneusi (Entbi); Encephalitozoon cuniculi (Enccu); Fusarium acaciae-mearnsii (Fusac); Gibberella fujikuroi (Gibfu); Gibberella zeae (Gibze); Homo sapiens (Homsa); Lachancea thermotolerans (Lacth); Magnaporthe oryzae (Magor); Mycosphaerella graminicola (Mycgr); Podospora anserina (Podan); Neurospora crassa (Neucr); Penicillium marneffei (Penma); Phycomyces blakesleeanus (Phybl); Pneumocystis carinii (Pneca); Pyrenopeziza brassicae (Pyrbr); Pyrenophora teres (Pyrte); Rhynchosporium secalis (Rhyse); Saccharomyces cerevisiae (Sacce); Schizosaccharomyces japonicus (Schja); Schizosaccharomyces pombe (Schpo); Sordaria macrospora (Sorma); Stemphylium sarciniforme (Stesa); Strongylocentrotus purpuratus (Strpu); Takifugu rubripes (Takru); Ustilago maydis (Ustma); Verticillium dahliae (Verda); Xenopus laevis (Xenla); and Zygosaccharomyces rouxii (Zygro). Numbers after species names indicate α1 proteins (1), MATA_HMG (2), MAT1-1-3 (3), SOX (4), HMGB-UBF_HMG (5) and other HMG domains (6–9). When more than one domain was present for the same species, the suffix a, b or c was used. Units indicate the number of amino acid changes per position. Species codes and accession numbers grouped by evolutionary affinity are listed in Table S2.