Plant-Symbiotic Fungi as Chemical Engineers: Multi-Genome Analysis of the Clavicipitaceae Reveals Dynamics of Alkaloid Loci
Figure 9
Loline alkaloid biosynthesis loci (LOL) in epichloae and the homologous loci in other Clavicipitaceae.
LOL genes are indicated by single letters, whereby F = lolF, C = lolC, and so forth. Features are indicated as in Figure 7. Double-slash marks (//) indicate sequence gaps within scaffolds of the assembled E. festucae E2368 genome sequence. Genes for the first fully cyclized intermediate, NANL, are indicated in blue, and those for subsequent chemical decorations are shown in red. The major pathway end-product for each strain is listed at the right of its map, abbreviated as indicated in Figure 4, and in bold for those confirmed in this study.