Lysosome-related organelles employ divergent mechanisms to modulate cytosolic zinc homeostasis

• Chaoyi Xie ,

  Contributed equally to this work with: Chaoyi Xie, Yi Luo

  Roles Conceptualization, Investigation, Validation, Visualization, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, Hubei, China

  https://orcid.org/0009-0005-8419-3528

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• Yi Luo ,

  Contributed equally to this work with: Chaoyi Xie, Yi Luo

  Roles Investigation, Validation, Visualization

  Affiliation Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, Hubei, China

  ⨯
• Yawen Zheng,

  Roles Investigation, Validation

  Affiliation Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, Hubei, China

  ⨯
• Bowen Liu,

  Roles Investigation

  Affiliation Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, Hubei, China

  https://orcid.org/0009-0002-7417-7186

  ⨯
• Shibo Song,

  Roles Visualization

  Affiliation Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, Hubei, China

  https://orcid.org/0009-0007-6388-3321

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• Jie Wei,

  Roles Investigation

  Affiliation Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, Hubei, China

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• Anbing Shi,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliations Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, Hubei, China, Cell Architecture Research Center, Huazhong University of Science and Technology, Wuhan, Hubei, China

  https://orcid.org/0000-0003-1128-2026

  ⨯
• Yanling Yan

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: yanyl@hust.edu.cn

  Affiliation Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, Hubei, China

  https://orcid.org/0000-0002-9145-1872

  ⨯