FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets

• Pravesh Parekh ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: praveshparekh@gmail.com (PP); andersmdale@gmail.com (AMD)

  Affiliations Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway, Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California, United States of America

  https://orcid.org/0000-0002-1930-1167

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• Nadine Parker,

  Roles Conceptualization, Methodology, Visualization, Writing – review & editing

  Affiliation Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway

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• Diliana Pecheva,

  Roles Methodology, Software, Writing – review & editing

  Affiliation Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California, United States of America

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• Evgeniia Frei,

  Roles Data curation, Investigation, Software, Writing – review & editing

  Affiliation Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway

  https://orcid.org/0009-0008-6405-9059

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• Marc Vaudel,

  Roles Data curation, Writing – review & editing

  Affiliations Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway, Computational Biology Unit, Department of Informatics, University of Bergen, Bergen, Norway, Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Bergen, Norway

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• Diana M. Smith,

  Roles Software, Writing – review & editing

  Affiliations Center for Human Development, University of California San Diego, La Jolla, California, United States of America, Medical Scientist Training Program, University of California San Diego, La Jolla, California, United States of America

  https://orcid.org/0000-0002-7484-0980

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• Alison Rigby,

  Roles Conceptualization, Methodology, Software, Supervision, Writing – review & editing

  Affiliation Neuroscience Graduate Program, University of California San Diego, La Jolla, California, United States of America

  https://orcid.org/0000-0003-2728-9310

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• Piotr Jahołkowski,

  Roles Data curation, Visualization, Writing – review & editing

  Affiliation Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway

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• Ida Elken Sønderby,

  Roles Resources, Writing – review & editing

  Affiliations Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway, Department of Medical Genetics, Oslo University Hospital & University of Oslo, Oslo, Norway

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• Viktoria Birkenæs,

  Roles Data curation, Writing – review & editing

  Affiliations Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway, PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway

  https://orcid.org/0000-0003-3194-1535

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• Nora Refsum Bakken,

  Roles Data curation, Writing – review & editing

  Affiliations Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway, PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway

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• Chun Chieh Fan,

  Roles Software, Writing – review & editing

  Affiliation Center for Population Neuroscience and Genetics, Laureate Institute for Brain Research, Tulsa, Oklahoma, United States of America

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• Carolina Makowski,

  Roles Writing – review & editing

  Affiliation Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, California, United States of America

  https://orcid.org/0000-0002-8816-4549

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• Jakub Kopal,

  Roles Software, Writing – review & editing

  Affiliation Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway

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• Robert Loughnan,

  Roles Writing – review & editing

  Affiliations Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California, United States of America, Population Neuroscience and Genetics Lab, University of California San Diego, La Jolla, California, United States of America

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• Donald J. Hagler Jr,

  Roles Writing – review & editing

  Affiliation Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California, United States of America

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• Dennis van der Meer,

  Roles Writing – review & editing

  Affiliation Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway

  https://orcid.org/0000-0002-0466-386X

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• Stefan Johansson,

  Roles Writing – review & editing

  Affiliations Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway, Department of Pediatrics and Adolescents, Haukeland University Hospital, Bergen, Norway

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• Pål Rasmus Njølstad,

  Roles Writing – review & editing

  Affiliations Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway, Department of Pediatrics and Adolescents, Haukeland University Hospital, Bergen, Norway

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• Terry L. Jernigan,

  Roles Resources, Writing – review & editing

  Affiliations Department of Radiology, School of Medicine, University of California San Diego, La Jolla, California, United States of America, Center for Human Development, University of California San Diego, La Jolla, California, United States of America, Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, California, United States of America, Department of Cognitive Science, University of California San Diego, La Jolla, California, United States of America

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• Wesley K. Thompson,

  Roles Methodology, Writing – review & editing

  Affiliation Center for Population Neuroscience and Genetics, Laureate Institute for Brain Research, Tulsa, Oklahoma, United States of America

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• Oleksandr Frei,

  Roles Conceptualization, Data curation, Methodology, Software, Supervision, Writing – review & editing

  Affiliations Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway, Department of Pharmacy, Section for Pharmacology and Pharmaceutical Biosciences, University of Oslo, Oslo, Norway

  https://orcid.org/0000-0002-6427-2625

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• Alexey A. Shadrin,

  Roles Writing – review & editing

  Affiliation Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway

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• Thomas E. Nichols,

  Roles Conceptualization, Methodology, Software, Supervision, Visualization, Writing – review & editing

  Affiliations Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom

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• Ole A. Andreassen,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway

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•  [ ... ],
• Anders M. Dale

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Visualization, Writing – review & editing

  * E-mail: praveshparekh@gmail.com (PP); andersmdale@gmail.com (AMD)

  Affiliations Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California, United States of America, University of California San Diego, La Jolla, California, United States of America, University of Oslo, Oslo, Norway

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