Comparative whole-genome analyses of articular chondrocytes and skin fibroblasts reveal distinct genome instability landscapes in mesenchymal cell types

• Safia Mahabub Sauty,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, North Carolina, United States of America

  https://orcid.org/0000-0002-1022-1822

  ⨯
• Jacqueline Shine,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0002-9640-4741

  ⨯
• Hamed Bostan,

  Roles Data curation, Formal analysis

  Affiliation Integrative Bioinformatics Support Group, Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, North Carolina, United States of America

  https://orcid.org/0000-0003-4102-807X

  ⨯
• Jian-Liang Li,

  Roles Supervision

  Affiliation Integrative Bioinformatics Support Group, Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, North Carolina, United States of America

  https://orcid.org/0000-0002-6487-081X

  ⨯
• Piotr A. Mieczkowski,

  Roles Data curation, Investigation

  Affiliation Department of Genetics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0003-2418-0096

  ⨯
• Richard F. Loeser,

  Roles Resources, Writing – review & editing

  Affiliations Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America, Division of Rheumatology, Allergy, and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0003-2832-6144

  ⨯
• Brian O. Diekman ,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: gordenin@niehs.nih.gov (DAG); bdiekman@email.unc.edu (BOD)

  Affiliations Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America, Division of Rheumatology, Allergy, and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America, Lampe Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, North Carolina, United States of America

  https://orcid.org/0000-0001-9055-4282

  ⨯
• Dmitry A. Gordenin

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: gordenin@niehs.nih.gov (DAG); bdiekman@email.unc.edu (BOD)

  Affiliation Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, North Carolina, United States of America

  https://orcid.org/0000-0002-8399-1836

  ⨯