Nebivolol suppresses glioblastoma progression via dual modulation of mitochondrial metabolism and AKT/mTOR/4EBP1 signaling axis

• Lingni Zhou ,

  Contributed equally to this work with: Lingni Zhou, Hongyu Che, Hongyan Jiang, Luxin Yin

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliations Department of Neurosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China, Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China, Department of Critical Care Medicine, Yancheng Third People’s Hospital, Yancheng, Jiangsu, China

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• Hongyu Che ,

  Contributed equally to this work with: Lingni Zhou, Hongyu Che, Hongyan Jiang, Luxin Yin

  Roles Data curation, Formal analysis, Methodology

  Affiliations Department of Neurosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China, Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China

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• Hongyan Jiang ,

  Contributed equally to this work with: Lingni Zhou, Hongyu Che, Hongyan Jiang, Luxin Yin

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliations Department of Neurosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China, Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China

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• Luxin Yin ,

  Contributed equally to this work with: Lingni Zhou, Hongyu Che, Hongyan Jiang, Luxin Yin

  Roles Funding acquisition, Resources

  Affiliations Department of Neurosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China, Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China

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• Yongang Jiang,

  Roles Data curation, Formal analysis

  Affiliation Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China

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• Yuhui Zhang,

  Roles Formal analysis, Methodology

  Affiliation Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China

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• Haoran Liang,

  Roles Formal analysis, Methodology

  Affiliation Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China

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• Rutong Yu,

  Roles Resources

  Affiliations Department of Neurosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China, Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China

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• Xu Zhang ,

  Roles Investigation, Project administration, Writing – review & editing

  ^* liuxuejiao0923@xzhmu.edu.cn (XL); zhangxu0502@sina.com (XZ)

  Affiliations Department of Neurosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China, Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China

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• Xuejiao Liu

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Writing – review & editing

  ^* liuxuejiao0923@xzhmu.edu.cn (XL); zhangxu0502@sina.com (XZ)

  Affiliations Department of Neurosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China, Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, China

  https://orcid.org/0009-0000-0206-2991

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