DNMT1 loss leads to hypermethylation of a subset of late replicating domains by DNMT3A

• Ioannis Kafetzopoulos,

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliations Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom, Current address: Altos Labs, Cambridge Institute, Cambridge, United Kingdom

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• Francesca Taglini,

  Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

  Affiliation Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom

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• Moira Pasquier,

  Roles Formal analysis

  Affiliation MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom

  https://orcid.org/0009-0007-1957-2120

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• Hazel Davidson-Smith,

  Roles Investigation

  Affiliation Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom

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• Christine J. Rodger,

  Roles Investigation, Methodology

  Affiliation MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom

  https://orcid.org/0000-0001-6318-7923

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• Lucia Puchades Gimeno,

  Roles Investigation, Methodology

  Affiliation MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom

  https://orcid.org/0009-0003-5271-7951

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• Andrew A. Malcolm,

  Roles Investigation, Methodology

  Affiliation Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom

  https://orcid.org/0000-0001-6240-7701

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• Duncan Sproul

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: d.sproul@ed.ac.uk

  Affiliation Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom

  https://orcid.org/0000-0001-6168-4563

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