Estimating the distribution of fitness effects of loss of heterozygosity (LOH) events using an engineered library of Saccharomyces cerevisiae

• Yi-Hong Ke,

  Roles Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-8435-082X

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• Michelle Orozco-Quime,

  Roles Investigation

  Affiliation Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0009-0005-8550-309X

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• Josh Bauman,

  Roles Investigation

  Affiliation Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Tamilie Carvalho,

  Roles Investigation

  Affiliations Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America, Institute for Global Change Biology, School for Environment and Sustainability, University of Michigan, Ann Arbor, Michigan, United States of America

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• Grant A. Landry,

  Roles Investigation

  Affiliation Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0009-0000-7577-8122

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• Shuhua Ge,

  Roles Investigation, Methodology

  Affiliation Technology Development and Transfer Center, Institute of Microbiology, Chinese Academy of Sciences, Chaoyang District, Beijing, China

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• Anuj Kumar,

  Roles Conceptualization, Project administration, Writing – review & editing

  Affiliation Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-8923-297X

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• Timothy Y. James

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: tyjames@umich.edu

  Affiliations Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America, Herbarium (MICH), University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-1123-5986

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