Chromatin insulators homie and nhomie can interact with distant copies either together or separately, with distinct outcomes for enhancer-promoter interactions

• Miki Fujioka,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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• Wenfan Ke,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

  https://orcid.org/0000-0002-7047-5445

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• Paul Schedl,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

  https://orcid.org/0000-0001-5704-2349

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• James B. Jaynes

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: james.jaynes@jefferson.edu

  Affiliation Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

  https://orcid.org/0000-0001-7943-794X

  ⨯