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Open Access
Peer-reviewed
Research Article
Tulp3 quantitative alleles titrate requirements for viability, brain development, and kidney homeostasis but do not suppress Zfp423 mutations in mice
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Corinne A. McCoy,
Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine, UC San Diego School of Medicine, La Jolla, California, United States of America
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Dorothy Concepcion,
Roles Data curation, Investigation, Methodology, Project administration, Writing – review & editing
Affiliation Department of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine, UC San Diego School of Medicine, La Jolla, California, United States of America
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Mark G. Mezody,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine, UC San Diego School of Medicine, La Jolla, California, United States of America
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Raquel Z. Lara,
Roles Investigation, Writing – review & editing
Current Address: University of Texas, Rio Grande Valley School of Medicine, Edinburg, Texas, United States of America
Affiliation Department of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine, UC San Diego School of Medicine, La Jolla, California, United States of America
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Ojas Deshpande,
Roles Investigation, Methodology, Writing – review & editing
Current Address: University of Arizona College of Medicine, Phoenix, Arizona, United States of America
Affiliation Department of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine, UC San Diego School of Medicine, La Jolla, California, United States of America
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Catherine Liang,
Roles Investigation, Writing – review & editing
Affiliation Department of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine, UC San Diego School of Medicine, La Jolla, California, United States of America
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Renee Long,
Roles Investigation, Methodology, Writing – review & editing
Current Address: Department of Dermatology, Stanford University School of Medicine, Redwood City, California, United States of America
Affiliation Department of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine, UC San Diego School of Medicine, La Jolla, California, United States of America
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Bruce A. Hamilton
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: bah@health.ucsd.edu
Affiliation Department of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine, UC San Diego School of Medicine, La Jolla, California, United States of America
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Tulp3 quantitative alleles titrate requirements for viability, brain development, and kidney homeostasis but do not suppress Zfp423 mutations in mice
- Corinne A. McCoy,
- Dorothy Concepcion,
- Mark G. Mezody,
- Raquel Z. Lara,
- Ojas Deshpande,
- Catherine Liang,
- Renee Long,
- Bruce A. Hamilton
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- Published: October 15, 2025
- https://doi.org/10.1371/journal.pgen.1011911