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Open Access
Peer-reviewed
Research Article
Probing the molecular determinants of Ty1 retrotransposon restriction specificity in yeast
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Sean L. Beckwith ,
Contributed equally to this work with: Sean L. Beckwith, Matthew A. Cottee
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
Current address: Department of Biology, Hope College, Holland, Michigan, United States of America
Affiliations Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, United States of America, Department of Biology, Hope College, Holland, Michigan, United States of America
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Matthew A. Cottee ,
Contributed equally to this work with: Sean L. Beckwith, Matthew A. Cottee
Roles Conceptualization, Formal analysis, Investigation, Validation, Visualization, Writing – review & editing
Current address: AstraZeneca, Discovery Centre, Cambridge, United Kingdom
Affiliation Macromolecular Structure Laboratory, The Francis Crick Institute, London, United Kingdom
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J. Adam Hannon-Hatfield,
Roles Conceptualization, Formal analysis, Investigation, Validation, Writing – review & editing
Current address: Department of Biochemistry, Emory School of Medicine, Emory University, Atlanta, Georgia, United States of America
Affiliation Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, United States of America
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Abigail C. Newman,
Roles Formal analysis, Investigation
Affiliation Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, United States of America
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Emma C. Walker,
Roles Formal analysis, Investigation
Affiliation Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, United States of America
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Justin R. Romero,
Roles Formal analysis, Investigation
Affiliation Department of Biology, Hope College, Holland, Michigan, United States of America
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Jonathan P. Stoye,
Roles Conceptualization, Supervision, Writing – review & editing
Affiliation Retrovirus-Host Interactions Laboratory. The Francis Crick Institute, London, United Kingdom
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Ian A. Taylor ,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: ian.taylor@crick.ac.uk (IAT); djgarf@uga.edu (DJG)
Affiliation Macromolecular Structure Laboratory, The Francis Crick Institute, London, United Kingdom
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David J. Garfinkel
Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing
* E-mail: ian.taylor@crick.ac.uk (IAT); djgarf@uga.edu (DJG)
Affiliation Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, United States of America
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Probing the molecular determinants of Ty1 retrotransposon restriction specificity in yeast
- Sean L. Beckwith,
- Matthew A. Cottee,
- J. Adam Hannon-Hatfield,
- Abigail C. Newman,
- Emma C. Walker,
- Justin R. Romero,
- Jonathan P. Stoye,
- Ian A. Taylor,
- David J. Garfinkel
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- Published: October 9, 2025
- https://doi.org/10.1371/journal.pgen.1011898