Role of Pcdh15 in the development of intrinsic polarity of inner ear hair cells

Raman Kaushik; Shivangi Pandey; Anubhav Prakash; Fenil Ganatra; Takaya Abe; Hiroshi Kiyonari; Raj K. Ladher

doi:10.1371/journal.pgen.1011825

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Open Access

Peer-reviewed

Research Article

Role of Pcdh15 in the development of intrinsic polarity of inner ear hair cells

Raman Kaushik,

Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, India

https://orcid.org/0000-0002-6953-2924

⨯
Shivangi Pandey,

Roles Investigation, Methodology, Writing – review & editing

Affiliation National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, India

https://orcid.org/0000-0003-1822-2528

⨯
Anubhav Prakash,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliations National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, India, Trivedi School of Biosciences, Ashoka University, Sonipat, Haryana, India

https://orcid.org/0000-0002-9774-8212

⨯
Fenil Ganatra,

Roles Investigation, Methodology

Affiliation National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, India

https://orcid.org/0009-0006-0936-0194

⨯
Takaya Abe,

Roles Methodology, Resources, Writing – review & editing

Affiliation Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo, Japan

https://orcid.org/0000-0001-5885-4875

⨯
Hiroshi Kiyonari,

Roles Methodology, Resources

Affiliation Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo, Japan

https://orcid.org/0000-0002-1509-8747

⨯
Raj K. Ladher

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: rajladher@ncbs.res.in

Affiliation National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, India

https://orcid.org/0000-0002-3613-9456

⨯

Role of Pcdh15 in the development of intrinsic polarity of inner ear hair cells

Raman Kaushik,
Shivangi Pandey,
Anubhav Prakash,
Fenil Ganatra,
Takaya Abe,
Hiroshi Kiyonari,
Raj K. Ladher

Published: August 13, 2025
https://doi.org/10.1371/journal.pgen.1011825

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Cell polarity
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Planar cell polarity
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Centrioles
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Organ of Corti
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