Maximal inhibitory effect of MOV10 on LINE-1 retrotransposition requires both the MOV10/LINE-1 association and granule formation

• Qian Liu ,

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Validation, Visualization, Writing – original draft

  ¶☯ These authors contributed equally to this work as first author.

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯
• Yaqi Liu ,

  Roles Conceptualization, Data curation, Visualization

  ¶☯ These authors contributed equally to this work as first author.

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯
• Yang Mao,

  Roles Formal analysis, Software

  Affiliation Department of Virus Research, Ningbo Municipal Center for Disease Control and prevention, Ningbo, China

  ⨯
• Dongrong Yi,

  Roles Formal analysis, Resources

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯
• Quanjie Li,

  Roles Formal analysis, Software

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯
• Jiwei Ding,

  Roles Investigation, Resources

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯
• Saisai Guo,

  Roles Resources, Validation

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯
• Yongxin Zhang,

  Roles Supervision

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯
• Jing Wang,

  Roles Investigation

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯
• Jianyuan Zhao,

  Roles Supervision

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯
• Ling Ma,

  Roles Formal analysis

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯
• Xiaozhong Peng ,

  Roles Project administration, Writing – review & editing

  * E-mail: pengxiaozhong@pumc.edu.cn (XP); shancen@imb.pumc.edu.cn (SC); lixiaoyu@imb.pumc.edu.cn (XL)

  Affiliation State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China

  ⨯
• Shan Cen ,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  * E-mail: pengxiaozhong@pumc.edu.cn (XP); shancen@imb.pumc.edu.cn (SC); lixiaoyu@imb.pumc.edu.cn (XL)

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  https://orcid.org/0000-0003-3358-0411

  ⨯
• Xiaoyu Li

  Roles Data curation, Funding acquisition, Methodology, Project administration, Writing – review & editing

  * E-mail: pengxiaozhong@pumc.edu.cn (XP); shancen@imb.pumc.edu.cn (SC); lixiaoyu@imb.pumc.edu.cn (XL)

  Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  ⨯