Early life starvation and Hedgehog-related signaling activate innate immunity downstream of daf-18/PTEN and lin-35/Rb causing developmental pathology in adult C. elegans

• Ivan B. Falsztyn,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliations Department of Biology, Duke University Box, Durham, North Carolina, United States of America, University Program in Genetics and Genomics, Duke School of Medicine, Durham, North Caroline, United States of America

  https://orcid.org/0000-0001-8624-4986

  ⨯
• James M. Jordan,

  Roles Conceptualization

  Current Address: Department of Biological Science, Florida State University, Tallahassee, Florida, United States of America

  Affiliation Department of Biology, Duke University Box, Durham, North Carolina, United States of America

  https://orcid.org/0000-0002-7620-462X

  ⨯
• Jingxian Chen,

  Roles Conceptualization

  Current Address: Institut Curie, Paris, France

  Affiliation Department of Biology, Duke University Box, Durham, North Carolina, United States of America

  https://orcid.org/0000-0002-1642-6060

  ⨯
• Winnie Zhao,

  Roles Investigation

  Affiliation Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

  ⨯
• Rojin Chitrakar,

  Roles Investigation

  Current Address: Sequencing and Genomic Technologies Shared Resource, Duke University, Durham, North Carolina, United States of America

  Affiliation Department of Biology, Duke University Box, Durham, North Carolina, United States of America

  ⨯
• Aaron W. Reinke,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

  https://orcid.org/0000-0001-7612-5342

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• L. Ryan Baugh

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: ryan.baugh@duke.edu

  Affiliations Department of Biology, Duke University Box, Durham, North Carolina, United States of America, University Program in Genetics and Genomics, Duke School of Medicine, Durham, North Caroline, United States of America

  https://orcid.org/0000-0003-2148-5492

  ⨯