An insulin-sensitive Drosophila insulin-like receptor mutant remodels methionine metabolism to extend lifespan

• Marc Tatar ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: marc_tatar@brown.edu (MT); aparkhitko@pitt.edu (AAP)

  Affiliation Department of Ecology, Evolution and Organismal Biology, The Center for the Biology of Aging, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0003-3232-6884

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• Wenjing Zheng,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Ecology, Evolution and Organismal Biology, The Center for the Biology of Aging, Brown University, Providence, Rhode Island, United States of America

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• Shweta Yadav,

  Roles Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Aging Institute of UPMC and the University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0001-9760-3382

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• Rochele Yamamoto,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Ecology, Evolution and Organismal Biology, The Center for the Biology of Aging, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0009-0008-2983-3061

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• Noelle Curtis-Joseph,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Ecology, Evolution and Organismal Biology, The Center for the Biology of Aging, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0003-2183-9238

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• Shengxi Li,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation State Key Laboratory of Common Mechanism Research for Major Disease, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Lin Wang,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation State Key Laboratory of Common Mechanism Research for Major Disease, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Andrey A. Parkhitko

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: marc_tatar@brown.edu (MT); aparkhitko@pitt.edu (AAP)

  Affiliation Aging Institute of UPMC and the University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0001-9852-8329

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