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Open Access
Peer-reviewed
Research Article
Shaker/Kv1 potassium channel SHK-1 protects against pathogen infection and oxidative stress in C. elegans
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Longjun Pu ,
Contributed equally to this work with: Longjun Pu, Jing Wang
Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing
* E-mail: longjun.pu@umu.se (LP); yqtang@fudan.edu.cn (Y-QT); sun.nyunt.wai@umu.se (SNW); changchun.chen@umu.se (CC)
Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, Umeå Centre for Molecular Medicine, Umeå University, Umeå, Sweden, Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden
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Jing Wang ,
Contributed equally to this work with: Longjun Pu, Jing Wang
Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization
Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, Umeå Centre for Molecular Medicine, Umeå University, Umeå, Sweden, Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden
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Lars Nilsson,
Roles Investigation, Validation
Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, Umeå Centre for Molecular Medicine, Umeå University, Umeå, Sweden, Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden
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Lina Zhao,
Roles Investigation, Validation
Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, Umeå Centre for Molecular Medicine, Umeå University, Umeå, Sweden, Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden
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Chloe Williams,
Roles Investigation
Affiliation Department of Medical and Translational Biology, Umeå University, Umeå, Sweden
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Guanqiao Chi,
Roles Investigation
Affiliation Institutes of Brain Science, Department of Orthodontics, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China
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Jonathan D Gilthorpe,
Roles Formal analysis, Methodology, Resources, Supervision, Writing – review & editing
Affiliation Department of Medical and Translational Biology, Umeå University, Umeå, Sweden
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Simon Tuck,
Roles Formal analysis, Investigation
Affiliation Department of Medical and Translational Biology, Umeå University, Umeå, Sweden
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Johan Henriksson,
Roles Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Software, Validation, Visualization
Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden, Integrated Science Lab (Icelab), Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden
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Yi-Quan Tang ,
Roles Formal analysis, Methodology, Validation
* E-mail: longjun.pu@umu.se (LP); yqtang@fudan.edu.cn (Y-QT); sun.nyunt.wai@umu.se (SNW); changchun.chen@umu.se (CC)
Affiliation Institutes of Brain Science, Department of Orthodontics, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China
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Sun Nyunt Wai ,
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing
* E-mail: longjun.pu@umu.se (LP); yqtang@fudan.edu.cn (Y-QT); sun.nyunt.wai@umu.se (SNW); changchun.chen@umu.se (CC)
Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden
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Changchun Chen
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing
* E-mail: longjun.pu@umu.se (LP); yqtang@fudan.edu.cn (Y-QT); sun.nyunt.wai@umu.se (SNW); changchun.chen@umu.se (CC)
Affiliations Department of Molecular Biology, Umeå University, Umeå, Sweden, Umeå Centre for Molecular Medicine, Umeå University, Umeå, Sweden, Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden
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Shaker/Kv1 potassium channel SHK-1 protects against pathogen infection and oxidative stress in C. elegans
- Longjun Pu,
- Jing Wang,
- Lars Nilsson,
- Lina Zhao,
- Chloe Williams,
- Guanqiao Chi,
- Jonathan D Gilthorpe,
- Simon Tuck,
- Johan Henriksson,
- Yi-Quan Tang
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- Published: February 6, 2025
- https://doi.org/10.1371/journal.pgen.1011554