Separable roles of the DNA damage response kinase Mec1ATR and its activator Rad24RAD17 during meiotic recombination

Margaret R. Crawford; Jon A. Harper; Tim J. Cooper; Marie-Claude Marsolier-Kergoat; Bertrand Llorente; Matthew J. Neale

doi:10.1371/journal.pgen.1011485

Loading metrics

Open Access

Peer-reviewed

Research Article

Separable roles of the DNA damage response kinase Mec1^ATR and its activator Rad24^RAD17 during meiotic recombination

Margaret R. Crawford,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, United Kingdom, Francis Crick Institute, London, United Kingdom

https://orcid.org/0000-0001-8369-3508

⨯
Jon A. Harper,

Roles Data curation, Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, United Kingdom

https://orcid.org/0000-0002-1765-9990

⨯
Tim J. Cooper,

Roles Formal analysis, Software

Affiliation Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, United Kingdom
⨯
Marie-Claude Marsolier-Kergoat,

Roles Methodology, Software

Affiliations Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-Saclay, Gif-sur-Yvette, France, UMR7206 Eco-Anthropology and Ethno-Biology, CNRS-MNHN-University Paris Diderot, Musée de l’Homme, Paris, France
⨯
Bertrand Llorente,

Roles Conceptualization, Methodology, Resources, Software, Writing – original draft, Writing – review & editing

Affiliation Cancer Research Centre of Marseille, CNRS, INSERM U1068, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France

https://orcid.org/0000-0002-6291-5797

⨯
Matthew J. Neale

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: m.neale@sussex.ac.uk

Affiliation Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, United Kingdom

https://orcid.org/0000-0002-6453-1877

⨯

Separable roles of the DNA damage response kinase Mec1^ATR and its activator Rad24^RAD17 during meiotic recombination

Margaret R. Crawford,
Jon A. Harper,
Tim J. Cooper,
Marie-Claude Marsolier-Kergoat,
Bertrand Llorente,
Matthew J. Neale

Published: December 9, 2024
https://doi.org/10.1371/journal.pgen.1011485

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Meiosis
Is the Subject Area "Meiosis" applicable to this article?

Thanks for your feedback.
Fungal spores
Is the Subject Area "Fungal spores" applicable to this article?

Thanks for your feedback.
Chromatids
Is the Subject Area "Chromatids" applicable to this article?

Thanks for your feedback.
Homologous recombination
Is the Subject Area "Homologous recombination" applicable to this article?

Thanks for your feedback.
DNA recombination
Is the Subject Area "DNA recombination" applicable to this article?

Thanks for your feedback.
Prophase
Is the Subject Area "Prophase" applicable to this article?

Thanks for your feedback.
DNA repair
Is the Subject Area "DNA repair" applicable to this article?

Thanks for your feedback.
Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.