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Open Access
Peer-reviewed
Research Article
Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes
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Laura Mora-Bitria,
Roles Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom, Systems Pharmacology and Medicine, Bayer AG, Leverkusen, Germany
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Bisrat J. Debebe,
Roles Formal analysis, Methodology, Software
Affiliation Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom
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Kelly L. Miners,
Roles Investigation
Affiliation Division of Infection and Immunity, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, United Kingdom
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Kristin Ladell,
Roles Investigation
Affiliation Division of Infection and Immunity, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, United Kingdom
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Charandeep Kaur,
Roles Investigation
Affiliation Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom
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James A. Traherne,
Roles Resources
Affiliation Immunology Division, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
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Wei Jiang,
Roles Resources
Affiliation Immunology Division, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
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David A. Price,
Roles Resources
Affiliations Division of Infection and Immunity, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, United Kingdom, Systems Immunity Research Institute, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, United Kingdom
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Linda Hadcocks,
Roles Investigation
Affiliation Institute for Infection and Immunity, St George’s, University of London, London, United Kingdom
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Nicholas A. R. McQuibban,
Roles Formal analysis
Affiliations Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom, Centre for Integrative Systems Biology and Bioinformatics (CISBIO), Department of Life Sciences, Imperial College London, London, United Kingdom
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John Trowsdale,
Roles Resources
Affiliation Immunology Division, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
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F Susan Wong,
Roles Resources
Affiliation Division of Infection and Immunity, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, United Kingdom
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Nikolas Pontikos,
Roles Resources
Affiliation UCL Institute of Ophthalmology, University College London, London, United Kingdom
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Christoph Niederalt,
Roles Funding acquisition, Project administration, Supervision
Affiliation Systems Pharmacology and Medicine, Bayer AG, Leverkusen, Germany
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Becca Asquith
Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: b.asquith@imperial.ac.uk
Affiliation Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom
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Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes
- Laura Mora-Bitria,
- Bisrat J. Debebe,
- Kelly L. Miners,
- Kristin Ladell,
- Charandeep Kaur,
- James A. Traherne,
- Wei Jiang,
- David A. Price,
- Linda Hadcocks,
- Nicholas A. R. McQuibban
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- Published: December 26, 2024
- https://doi.org/10.1371/journal.pgen.1011456