Disentangling the consequences of type 2 diabetes on targeted metabolite profiles using causal inference and interaction QTL analyses

• Ozvan Bocher ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: ozvan.bocher@helmholtz-munich.de

  Affiliation Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany

  https://orcid.org/0000-0002-2467-9236

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• Archit Singh,

  Roles Data curation, Writing – review & editing

  Affiliations Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany, Munich School for Data Science (MUDS), Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany, Technical University of Munich (TUM), TUM School of Medicine and Health, Graduate School of Experimental Medicine, Munich, Germany

  https://orcid.org/0000-0002-3983-6126

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• Yue Huang,

  Roles Data curation, Writing – review & editing

  Affiliations Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany, Technical University of Munich (TUM), TUM School of Medicine and Health, Graduate School of Experimental Medicine, Munich, Germany

  https://orcid.org/0000-0003-1671-7017

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• Urmo Võsa,

  Roles Formal analysis, Resources, Writing – review & editing

  Affiliation Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

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• Ene Reimann,

  Roles Data curation, Writing – review & editing

  Affiliations Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany, Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

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• Ana Arruda,

  Roles Conceptualization, Writing – review & editing

  Affiliations Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany, Munich School for Data Science (MUDS), Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany, Technical University of Munich (TUM), TUM School of Medicine and Health, Graduate School of Experimental Medicine, Munich, Germany

  https://orcid.org/0000-0002-6550-9794

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• Andrei Barysenska,

  Roles Data curation, Writing – review & editing

  Affiliation Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany

  https://orcid.org/0000-0002-9571-6292

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• Anastassia Kolde,

  Roles Data curation, Resources, Writing – review & editing

  Affiliations Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia, Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia

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• Nigel W. Rayner,

  Roles Resources, Writing – review & editing

  Affiliation Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany

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• Estonian Biobank research team ,

  ¶Membership of Estonian Biobank research team is provided in the Acknowledgements

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• Tõnu Esko,

  Roles Resources, Writing – review & editing

  Affiliation Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

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• Reedik Mägi,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

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• Eleftheria Zeggini

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Institute of Translational Genomics, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany, TUM school of medicine and health, Technical University Munich and Klinikum Rechts der Isar, Munich, Germany

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