Single-cell analysis identifies PLK1 as a driver of immunosuppressive tumor microenvironment in LUAD

• Yifan Kong ,

  Contributed equally to this work with: Yifan Kong, Chaohao Li, Jinpeng Liu, Sai Wu

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America

  ⨯
• Chaohao Li ,

  Contributed equally to this work with: Yifan Kong, Chaohao Li, Jinpeng Liu, Sai Wu

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America

  ⨯
• Jinpeng Liu ,

  Contributed equally to this work with: Yifan Kong, Chaohao Li, Jinpeng Liu, Sai Wu

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – review & editing

  Affiliation Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America

  ⨯
• Sai Wu ,

  Contributed equally to this work with: Yifan Kong, Chaohao Li, Jinpeng Liu, Sai Wu

  Roles Data curation, Formal analysis, Investigation, Project administration, Validation, Visualization

  Affiliation Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America

  ⨯
• Min Zhang,

  Roles Project administration, Resources

  Affiliation Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America

  ⨯
• Derek B. Allison,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Validation, Visualization

  Affiliations Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America, Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky, United States of America

  https://orcid.org/0000-0002-5119-2474

  ⨯
• Faisal Hassan,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Validation, Visualization

  Affiliation Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky, United States of America

  ⨯
• Daheng He,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Validation, Visualization

  Affiliation Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America

  https://orcid.org/0000-0003-0399-2466

  ⨯
• Xinyi Wang,

  Roles Project administration, Resources

  Affiliation Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America

  https://orcid.org/0000-0002-8869-8292

  ⨯
• Fengyi Mao,

  Roles Project administration, Resources

  Affiliation Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America

  ⨯
• Qiongsi Zhang,

  Roles Project administration, Resources

  Affiliation Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America

  ⨯
• Yanquan Zhang,

  Roles Conceptualization, Resources, Supervision

  Affiliation Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America

  ⨯
• Zhiguo Li,

  Roles Conceptualization, Methodology, Resources

  Affiliation Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America

  ⨯
• Chi Wang,

  Roles Conceptualization, Methodology, Resources, Software, Supervision

  Affiliations Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America, Department of Biostatistics, University of Kentucky, Lexington, Kentucky, United States of America

  ⨯
• Xiaoqi Liu

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: xiaoqi.liu@uky.edu

  Affiliations Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America, Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America

  https://orcid.org/0000-0002-6613-1746

  ⨯