Autophagic dysfunction and gut microbiota dysbiosis cause chronic immune activation in a Drosophila model of Gaucher disease

• Magda L. Atilano ,

  Contributed equally to this work with: Magda L. Atilano, Alexander Hull

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation UCL Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom

  https://orcid.org/0000-0002-3819-2023

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• Alexander Hull ,

  Contributed equally to this work with: Magda L. Atilano, Alexander Hull

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Visualization, Writing – review & editing

  Affiliation UCL Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom

  https://orcid.org/0000-0002-9700-4926

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• Catalina-Andreea Romila,

  Roles Formal analysis

  Affiliation UCL Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom

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• Mirjam L. Adams,

  Roles Investigation, Methodology

  Affiliation UCL Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom

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• Jacob Wildfire,

  Roles Investigation, Methodology

  Affiliation UCL Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom

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• Enric Ureña,

  Roles Investigation, Methodology

  Affiliation UCL Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom

  https://orcid.org/0000-0003-4873-4735

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• Miranda Dyson,

  Roles Investigation

  Affiliation UCL Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom

  https://orcid.org/0000-0003-0845-662X

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• Jorge Ivan-Castillo-Quan,

  Roles Visualization

  Affiliation Section on Islet Cell & Regenerative Biology, Joslin Diabetes Center and Department of Genetics, Harvard Medical School, Boston, United States of America

  https://orcid.org/0000-0002-6324-2854

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• Linda Partridge,

  Roles Writing – review & editing

  Affiliation UCL Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom

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• Kerri J. Kinghorn

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: k.kinghorn@ucl.ac.uk

  Affiliation UCL Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom

  https://orcid.org/0000-0003-2048-4332

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