Searching across-cohort relatives in 54,092 GWAS samples via encrypted genotype regression

• Qi-Xin Zhang,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Institute of Bioinformatics, Zhejiang University, Hangzhou, Zhejiang, China, Center for Reproductive Medicine, Department of Genetic and Genomic Medicine, and Clinical Research Institute, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China

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• Tianzi Liu,

  Roles Data curation, Formal analysis, Validation, Writing – review & editing

  Affiliations CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China

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• Xinxin Guo,

  Roles Data curation, Formal analysis, Validation, Writing – review & editing

  Affiliation School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China

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• Jianxin Zhen,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation Central Laboratory, Shenzhen Baoan Women’s and Children’s Hospital, Shenzhen, Guangdong, China

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• Meng-yuan Yang,

  Roles Data curation, Formal analysis, Validation, Writing – review & editing

  Affiliation Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China

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• Saber Khederzadeh,

  Roles Data curation, Writing – review & editing

  Affiliation Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China

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• Fang Zhou,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China

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• Xiaotong Han,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, Guangdong, China

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• Qiwen Zheng,

  Roles Data curation, Writing – review & editing

  Affiliation CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China

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• Peilin Jia,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China

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• Xiaohu Ding,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, Guangdong, China

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• Mingguang He,

  Roles Data curation, Resources, Writing – review & editing

  Affiliations State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, Guangdong, China, Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia, Ophthalmology, Department of Surgery, University of Melbourne, Melbourne, Victoria, Australia

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• Xin Zou,

  Roles Investigation, Software, Writing – review & editing

  Affiliation State Key Laboratory of CAD & GC, Zhejiang University, Hangzhou, Zhejiang, China

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• Jia-Kai Liao,

  Roles Visualization, Writing – review & editing

  Affiliations School of Mathematics and Statistics and Research Institute of Mathematical Sciences (RIMS), Jiangsu Provincial Key Laboratory of Educational Big Data Science and Engineering, Jiangsu Normal University, Xuzhou, Jiangsu, China, Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, Zhejiang, China

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• Hongxin Zhang,

  Roles Validation, Writing – review & editing

  Affiliation State Key Laboratory of CAD & GC, Zhejiang University, Hangzhou, Zhejiang, China

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• Ji He,

  Roles Funding acquisition, Validation, Writing – review & editing

  Affiliation Department of Neurology, Peking University Third Hospital, Beijing, China

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• Xiaofeng Zhu,

  Roles Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Daru Lu,

  Roles Data curation, Resources, Writing – review & editing

  Affiliations State Key Laboratory of Genetic Engineering and MOE Engineering Research Center of Gene Technology, School of Life Sciences and Zhongshan Hospital, Fudan University, Shanghai, China, NHC Key Laboratory of Birth Defects and Reproductive Health, Chongqing Population and Family Planning Science and Technology Research Institute, Chongqing, China

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• Hongyan Chen,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China

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• Changqing Zeng,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliations CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, Henan Academy of Sciences, Zhengzhou, Henan, China

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• Fan Liu,

  Roles Data curation, Funding acquisition, Resources, Writing – review & editing

  Affiliations CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, Department of Forensic Sciences, College of Criminal Justice, Naif Arab University of Security Sciences, Riyadh, Kingdom of Saudi Arabia

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• Hou-Feng Zheng,

  Roles Funding acquisition, Resources, Validation, Writing – review & editing

  Affiliation Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China

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• Siyang Liu,

  Roles Data curation, Funding acquisition, Resources, Validation, Writing – review & editing

  Affiliation School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China

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• Hai-Ming Xu,

  Roles Resources, Software, Supervision, Writing – review & editing

  Affiliation Institute of Bioinformatics, Zhejiang University, Hangzhou, Zhejiang, China

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•  [ ... ],
• Guo-Bo Chen

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: chenguobo@gmail.com

  Affiliations Center for Reproductive Medicine, Department of Genetic and Genomic Medicine, and Clinical Research Institute, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China, Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Hangzhou, Zhejiang, China

  https://orcid.org/0000-0001-5475-8237

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