Methods for mediation analysis with high-dimensional DNA methylation data: Possible choices and comparisons

• Dylan Clark-Boucher,

  Roles Conceptualization, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biostatistics, Harvard T.H. Chan School of Public Health; Boston, Massachusetts, United States of America

  https://orcid.org/0000-0001-7334-2966

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• Xiang Zhou,

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Biostatistics, University of Michigan; Ann Arbor, Michigan, United States of America

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• Jiacong Du,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Biostatistics, University of Michigan; Ann Arbor, Michigan, United States of America

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• Yongmei Liu,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Medicine, Divisions of Cardiology and Neurology, Duke University Medical Center; Durham, North Carolina, United States of America

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• Belinda L. Needham,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Epidemiology, University of Michigan; Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0001-5939-2027

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• Jennifer A. Smith,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Epidemiology, University of Michigan; Ann Arbor, Michigan, United States of America, Survey Research Center, Institute for Social Research, University of Michigan; Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-3575-5468

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• Bhramar Mukherjee

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: bhramar@umich.edu

  Affiliations Department of Biostatistics, University of Michigan; Ann Arbor, Michigan, United States of America, Department of Epidemiology, University of Michigan; Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0003-0118-4561

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