Meta-analysis of genome-wide association studies of gestational duration and spontaneous preterm birth identifies new maternal risk loci

• Anu Pasanen ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: anu.pasanen@oulu.fi

  Affiliation Research Unit of Clinical Medicine, Medical Research Center Oulu, University of Oulu, and Department of Children and Adolescents, Oulu University Hospital, Oulu, Finland

  https://orcid.org/0000-0001-7460-5086

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• Minna K. Karjalainen,

  Roles Conceptualization, Data curation, Investigation, Writing – review & editing

  Affiliation Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland

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• FinnGen ,

  ¶Contributors of FinnGen are listed in S1 Acknowledgements.

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• Ge Zhang,

  Roles Validation, Writing – review & editing

  Affiliation Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, Center for Prevention of Preterm Birth, Perinatal Institute and March of Dimes Prematurity Research Center Ohio Collaborative, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

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• Heli Tiensuu,

  Roles Writing – review & editing

  Affiliation Research Unit of Clinical Medicine, Medical Research Center Oulu, University of Oulu, and Department of Children and Adolescents, Oulu University Hospital, Oulu, Finland

  https://orcid.org/0000-0002-9384-8435

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• Antti M. Haapalainen,

  Roles Writing – review & editing

  Affiliation Research Unit of Clinical Medicine, Medical Research Center Oulu, University of Oulu, and Department of Children and Adolescents, Oulu University Hospital, Oulu, Finland

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• Marja Ojaniemi,

  Roles Conceptualization, Writing – review & editing

  Affiliation Research Unit of Clinical Medicine, Medical Research Center Oulu, University of Oulu, and Department of Children and Adolescents, Oulu University Hospital, Oulu, Finland

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• Bjarke Feenstra,

  Roles Validation, Writing – review & editing

  Affiliation Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark

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• Bo Jacobsson,

  Roles Validation, Writing – review & editing

  Affiliations Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Institute of Clinical Science, University of Gothenburg, Gothenburg, Sweden, Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway

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• Aarno Palotie,

  Roles Conceptualization, Resources

  Affiliations Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland, Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Psychiatric & Neurodevelopmental Genetics Unit, Department of Psychiatry, Analytic and Translational Genetics Unit, Department of Medicine, and the Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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• Hannele Laivuori,

  Roles Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland, Center for Child, Adolescent, and Maternal Health Research, Faculty of Medicine and Health Technology, University of Tampere, Tampere, Finland, Department of Obstetrics and Gynecology, Tampere University Hospital, Tampere, Finland

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• Louis J. Muglia,

  Roles Conceptualization

  Affiliations Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, Center for Prevention of Preterm Birth, Perinatal Institute and March of Dimes Prematurity Research Center Ohio Collaborative, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America, Burroughs Wellcome Fund, Research Triangle Park, Durham, North Carolina, United States of America

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• Mika Rämet ,

  Contributed equally to this work with: Mika Rämet, Mikko Hallman

  Roles Conceptualization, Funding acquisition, Supervision

  Affiliations Research Unit of Clinical Medicine, Medical Research Center Oulu, University of Oulu, and Department of Children and Adolescents, Oulu University Hospital, Oulu, Finland, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland

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• Mikko Hallman

  Contributed equally to this work with: Mika Rämet, Mikko Hallman

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision

  Affiliation Research Unit of Clinical Medicine, Medical Research Center Oulu, University of Oulu, and Department of Children and Adolescents, Oulu University Hospital, Oulu, Finland

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