Uncovering associations between pre-existing conditions and COVID-19 Severity: A polygenic risk score approach across three large biobanks

• Lars G. Fritsche ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: larsf@umich.edu (LGF); bhramar@umich.edu (BM)

  Current address: Department of Biostatistics, School of Public Health University of Michigan, 1415 Washington Heights, SPH Tower Room 4633, Ann Arbor, Michigan 48109, United States of America

  Affiliations Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America, Center for Precision Health Data Science, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-2110-1690

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• Kisung Nam,

  Roles Formal analysis, Software, Visualization, Writing – review & editing

  Affiliation Graduate School of Data Science, Seoul National University, Seoul, South Korea

  https://orcid.org/0000-0002-7317-092X

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• Jiacong Du,

  Roles Writing – original draft, Writing – review & editing

  Affiliations Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America, Center for Precision Health Data Science, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-7768-9083

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• Ritoban Kundu,

  Roles Writing – review & editing

  Affiliations Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America, Center for Precision Health Data Science, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0003-0967-6755

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• Maxwell Salvatore,

  Roles Writing – review & editing

  Affiliations Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America, Center for Precision Health Data Science, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-3659-1514

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• Xu Shi,

  Roles Writing – review & editing

  Affiliation Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America

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• Seunggeun Lee,

  Roles Supervision, Writing – review & editing

  Affiliation Graduate School of Data Science, Seoul National University, Seoul, South Korea

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• Stephen Burgess,

  Roles Writing – review & editing

  Affiliations MRC Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom, Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom

  https://orcid.org/0000-0001-5365-8760

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• Bhramar Mukherjee

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: larsf@umich.edu (LGF); bhramar@umich.edu (BM)

  Affiliations Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America, Center for Precision Health Data Science, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America, Michigan Institute for Data Science, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0003-0118-4561

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