Neutrophil extracellular trap formation and gene programs distinguish TST/IGRA sensitization outcomes among Mycobacterium tuberculosis exposed persons living with HIV

• Elouise E. Kroon ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing – original draft

  * E-mail: elouise_k@sun.ac.za

  Affiliation DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa

  https://orcid.org/0000-0002-8551-3301

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• Wilian Correa-Macedo,

  Roles Formal analysis, Writing – review & editing

  Affiliations Program in Infectious Diseases and Immunity in Global Health, The Research Institute of the McGill University Health Centre, Montréal, Canada, McGill International TB Centre, McGill University, Montréal, Canada, Department of Biochemistry, McGill University, Montréal, Canada

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• Rachel Evans,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliations Infectious Diseases and Immune Defence Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia, Department Medical Biology (WEHI), Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Australia

  https://orcid.org/0009-0004-7956-5481

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• Allison Seeger,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Observatory, South Africa

  https://orcid.org/0000-0002-5332-3722

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• Lize Engelbrecht,

  Roles Data curation, Formal analysis, Methodology, Visualization, Writing – review & editing

  Affiliation Central Analytical Facilities, Microscopy Unit, Stellenbosch University, Cape Town, South Africa

  https://orcid.org/0000-0002-4518-7011

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• Jurgen A. Kriel,

  Roles Data curation, Formal analysis, Visualization, Writing – review & editing

  Affiliation Central Analytical Facilities, Microscopy Unit, Stellenbosch University, Cape Town, South Africa

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• Ben Loos,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Physiological Sciences, Stellenbosch University, Stellenbosch, South Africa

  https://orcid.org/0000-0002-5517-373X

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• Naomi Okugbeni,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliations DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa, South African Medical Research Council Genomics Platform, Tygerberg, South Africa

  https://orcid.org/0000-0003-3915-6152

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• Marianna Orlova,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Writing – review & editing

  Affiliations Program in Infectious Diseases and Immunity in Global Health, The Research Institute of the McGill University Health Centre, Montréal, Canada, McGill International TB Centre, McGill University, Montréal, Canada, Department of Biochemistry, McGill University, Montréal, Canada

  https://orcid.org/0000-0002-8108-938X

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• Pauline Cassart,

  Roles Data curation, Writing – review & editing

  Affiliations Program in Infectious Diseases and Immunity in Global Health, The Research Institute of the McGill University Health Centre, Montréal, Canada, McGill International TB Centre, McGill University, Montréal, Canada

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• Craig J. Kinnear,

  Roles Data curation, Funding acquisition, Writing – review & editing

  Affiliations DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa, South African Medical Research Council Genomics Platform, Tygerberg, South Africa

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• Gerard C. Tromp,

  Roles Formal analysis, Methodology, Supervision, Writing – review & editing

  Affiliations DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa, Centre for Bioinformatics and Computational Biology, University of Stellenbosch, Cape Town, South Africa, SAMRC-SHIP South African Tuberculosis Bioinformatics Initiative (SATBBI), Center for Bioinformatics and Computational Biology, Cape Town, South Africa

  https://orcid.org/0000-0002-7761-0806

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• Marlo Möller,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa, Centre for Bioinformatics and Computational Biology, University of Stellenbosch, Cape Town, South Africa

  https://orcid.org/0000-0002-0805-6741

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• Robert J. Wilkinson,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  Affiliations Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Observatory, South Africa, Department of Infectious Diseases, Imperial College London, London, United Kingdom, The Francis Crick Institute, London, United Kingdom

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• Anna K. Coussens,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Visualization, Writing – review & editing

  Affiliations Infectious Diseases and Immune Defence Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia, Department Medical Biology (WEHI), Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Australia, Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Observatory, South Africa

  https://orcid.org/0000-0002-7086-2621

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• Erwin Schurr,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – review & editing

  Affiliations Program in Infectious Diseases and Immunity in Global Health, The Research Institute of the McGill University Health Centre, Montréal, Canada, McGill International TB Centre, McGill University, Montréal, Canada, Department of Biochemistry, McGill University, Montréal, Canada

  https://orcid.org/0000-0002-2640-536X

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•  [ ... ],
• Eileen G. Hoal

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Visualization, Writing – review & editing

  Affiliation DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa

  https://orcid.org/0000-0002-6444-5688

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